Clexane 20mg Injection: See how to use, side effects, prices and substitutes | 1mg (2023)

FAQs

What are the side effects of Clexane 20MG? ›

Are there any side effects? Less serious side effects include pain, bruising, bleeding, swelling, itch, or rash at the injection site. Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness.

The cost for enoxaparin injectable solution (40 mg/0.4 mL) is around $12 for a supply of 0.4 milliliters, depending on the pharmacy you visit.

Bleeding is the most common side effect of clexane therapy. You can make the risk of bleeding much smaller by injecting the correct dose of clexane and having blood tests when instructed.

CLEXANE 20MG INJECTION(PFS) is an anticoagulant used to treat and prevent blood clots in the body. It works by stopping the blood clots formation and prevents the existing blood clots from growing bigger in size.

It can cause a rapid decrease in blood pressure, which may be dangerous to the patient.

Clexane is a Prescription Medicine for the treatment of blood clots and certain types of heart disease (angina & heart attacks) when used with aspirin. It is also used to prevent blood clots forming after an operation, during hospitalisation or during haemodialysis.

Are there any alternatives to clexane injections? During pregnancy there is no alternative treatment for a DVT. After your baby is born Warfarin tablets may be an appropriate alternative for you. Compression stockings may be prescribed to reduce your risk of developing a clot but they will not prevent it.

Enoxaparin is available as an injectable medicine that helps prevent blood clots in the legs and other parts of the body.

Direct subcutaneous injection should be given into a subcutaneous tissue skinfold of the abdomen or the upper-outer aspect of the thigh. The skinfold should be held throughout the injection. After removal of the needle, do not rub the site. Rather, place firm, even pressure to the site of injection for 1-5 minutes.

The recommended dose of CLEXANE is 40 mg once daily by subcutaneous injection. Treatment with CLEXANE is prescribed for a minimum of 6 days and continued until the return to full ambulation, for a maximum of 14 days.

Who needs Clexane injection? ›

When do I need Clexane? Clexane is used when the risk of having a blood clot is very high and the INR is below the therapeutic (target) range. Temporarily using Clexane as treatment in place of warfarin is commonly known as 'bridging'.

The usual dose is 1 mg per kg of body weight twice per day. Your doctor may change this dose as needed.

Make sure you take the clexane at the same time every day. If you need to have an injection twice a day then give the first dose in the morning and second dose 12 hours later. Sit or lie in a comfortable position so you are relaxed.

Response and effectiveness. The average time to peak effects on various clotting factors is anti-Xa (3 hours), anti-IIa (4 hours), and Heptest (2.5 hours). Activity against anti-Xa persists for about 12 hours following a once-daily dose of enoxaparin 40mg.

Bananas are high in potassium which is not good for certain medications. Try not to eat bananas or oranges if you take ACE inhibitors such as captopril, enalapril and fosinopril among others. ACE inhibitors lower blood pressure and treat heart failure by opening up blood vessels, so blood flows more efficiently.

Alcohol may interfere with the action of certain medications, including blood thinners. Doctors recommend that people taking warfarin or drugs containing acetylsalicylic acid limit their intake of alcohol. Occasional, moderate alcohol use should be safe for most people who are taking blood thinners.

All the fruits in the berry-family, including strawberries, cranberries, and blueberries are significant blood thinners. Oranges, tangerines, cherries, raisins, prunes, pineapples, and tomatoes work in the same manner.

Anticoagulants (applies to Clexane) liver disease

Major Potential Hazard, Low plausibility. Anticoagulants should be given with extreme caution to patients at increased risk for hemorrhage, including patients who have severe liver disease with impaired hemostasis.

Injections continue until at least 12 weeks gestation. The research suggests a 53% pregnancy rate. We still see that combination, Clexane and Prednisone, in many of our patients' protocols.

Anticoagulants. Anticoagulants, such as heparin, warfarin, dabigatran, apixaban, and rivaroxaban, are medications that thin the blood and help to dissolve blood clots.

Can I inject Clexane myself? ›

Lie down or sit in a comfortable position and gently pinch a skin fold at the injection site between your thumb and index finger. Insert the needle into the skin fold at a 90° angle and press the plunger until all the medicine is injected. Do not let go of the skin fold while you are injecting.

Do not use Clexane Syringes if: you are allergic to: enoxaparin sodium or any of the other ingredients of this medicine (listed in section 6) heparin or other low molecular weight heparins such as nadroparin, tinzaparin or dalteparin.

Side effects

Mild injection site reaction – ask your nurse or pharmacist for ways you might be able to reduce pain and irritation at the injection site. Allergic reaction – this includes shortness of breath, swelling and rashes.

A new study published in November 2022 in Annals of Internal Medicine found apibaxan to be the safest blood thinner among DOACs, including dabigatran, edoxaban and rivaroxaban. Apibaxan was associated with the lowest risk of gastrointestinal bleeding.

Clexane should never be injected into muscle as bleeding into the muscle may occur. By gently pinching the skin between your fingers throughout the injection, the medicine only enters fatty tissue and not muscle.

Aside from bleeding-related issues, there are several side effects that have been linked to blood thinners, such as nausea and low counts of cells in your blood. Low blood cell count can cause fatigue, weakness, dizziness and shortness of breath.

Lovenox is available in all EU countries. It is also available under other trade names: Clexane, Clexane T, Clexane Forte, Klexane, Qualiop, Enoxaparin Sanofi and Enoxaparine Sanofi.

Don't put CLEXANE in the fridge or the freezer – keep it at room temperature.

Which is better Clexane or heparin? ›

Heparin has a shorter half-life of 45 minutes, while enoxaparin has a half-life of four to five hours. Heparin is usually given in the hospital setting where it can be more closely monitored and is often used IV for emergencies. Enoxaparin is safe to give in the hospital and at home.

Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Enoxaparin may cause bleeding problems.

Inject your Clexane dose at the same time each day. Injection site: Change injection sites each time to stop your skin from hardening. Missed dose: If it is nearly time for your next dose, skip the missed dose and inject your next dose at the usual time. Otherwise, inject the missed dose as soon as possible.

Clexane (also known as enoxaparin) is a type of medicine called a low molecular weight heparin (LMWH). It is an injection which thins your blood and reduces the risk of developing further blood clots (thrombosis or pulmonary embolus).

Combining these medications can increase the risk of bleeding complications. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

Clexane is given either once or twice daily, depending on the underlying medical condition. Patients with mechanical heart valves are more likely to need an injection both morning and night.

Response and effectiveness. The average time to peak effects on various clotting factors is anti-Xa (3 hours), anti-IIa (4 hours), and Heptest (2.5 hours). Activity against anti-Xa persists for about 12 hours following a once-daily dose of enoxaparin 40mg.

Because you are taking a blood thinner, you should try not to hurt yourself and cause bleeding. You need to be careful when you use knives, scissors, razors, or any sharp object that can make you bleed. You also need to avoid activities and sports that could cause injury. Swimming and walking are safe activities.

If you stop taking the drug suddenly or don't take it at all: You'll have a higher risk for a blood clot. This could lead to serious problems, such as a stroke or death. Take this drug on the schedule set by your doctor. Don't stop taking it without speaking with your doctor first.

Anticoagulants (applies to Clexane) liver disease

Major Potential Hazard, Low plausibility. Anticoagulants should be given with extreme caution to patients at increased risk for hemorrhage, including patients who have severe liver disease with impaired hemostasis.

Who needs Clexane? ›

Clexane is often prescribed after operations (surgeries) such as hip or knee surgery, or abdominal surgery, when your risk of getting blood clots is increased. Clexane is also used if a blood clot has already formed in your heart (heart attack), leg (deep vein thrombosis) or lungs (pulmonary embolism).

Ques: Should I use Clexane 40 MG Injection empty stomach, before food or after food? Ans: This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach.